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Development of CD44E/s dual-targeting DNA aptamer as nanoprobe to deliver treatment in hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) is the predominant subtype of liver cancer with an extraordinary high mortality. Resistance to systemic therapy is a major cause of inferior clinical outcome in most patients with HCC. CD44 is a transmembrane cell-surface glycoprotein that is characterized...

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Detalles Bibliográficos
Autores principales: Lo, Cario Wing-Sze, Chan, Cecilia Ka Wing, Yu, Jianqing, He, Mian, Choi, Chung Hang Jonathan, Lau, James Yun Wong, Wong, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671951/
https://www.ncbi.nlm.nih.gov/pubmed/34976591
http://dx.doi.org/10.7150/ntno.62639