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Development of CD44E/s dual-targeting DNA aptamer as nanoprobe to deliver treatment in hepatocellular carcinoma
Background: Hepatocellular carcinoma (HCC) is the predominant subtype of liver cancer with an extraordinary high mortality. Resistance to systemic therapy is a major cause of inferior clinical outcome in most patients with HCC. CD44 is a transmembrane cell-surface glycoprotein that is characterized...
Autores principales: | Lo, Cario Wing-Sze, Chan, Cecilia Ka Wing, Yu, Jianqing, He, Mian, Choi, Chung Hang Jonathan, Lau, James Yun Wong, Wong, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671951/ https://www.ncbi.nlm.nih.gov/pubmed/34976591 http://dx.doi.org/10.7150/ntno.62639 |
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