Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study

OBJECTIVE: To determine whether CYP2C19 loss-of-function (LoF) alleles increase risk of ischaemic stroke and myocardial infarction (MI) in UK primary care patients prescribed clopidogrel. DESIGN: Retrospective cohort analysis. SETTING: Primary care practices in the UK from January 1999 to September...

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Detalles Bibliográficos
Autores principales: Pilling, Luke C, Türkmen, Deniz, Fullalove, Hannah, Atkins, Janice L, Delgado, Joao, Kuo, Chia-Ling, Kuchel, George A, Ferrucci, Luigi, Bowden, Jack, Masoli, Jane A H, Melzer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671970/
https://www.ncbi.nlm.nih.gov/pubmed/34903548
http://dx.doi.org/10.1136/bmjopen-2021-053905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671970/
https://www.ncbi.nlm.nih.gov/pubmed/34903548
http://dx.doi.org/10.1136/bmjopen-2021-053905

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