Distinct exhaustion features of T lymphocytes shape the tumor-immune microenvironment with therapeutic implication in patients with non-small-cell lung cancer

BACKGROUND: Reinvigoration of T-cell exhaustion with antibodies has shown promising efficacy in patients with non-small-cell lung cancer (NSCLC). However, the characteristics of T-cell exhaustion with regard to tumor-infiltrating lymphocytes (TILs) are poorly elucidated in NSCLC. Here, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Chang Gon, Kim, Gamin, Kim, Kyung Hwan, Park, Seyeon, Shin, Sunhye, Yeo, Dahee, Shim, Hyo Sup, Yoon, Hong In, Park, Seong Yong, Ha, Sang-Jun, Kim, Hye Ryun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671984/
https://www.ncbi.nlm.nih.gov/pubmed/34907028
http://dx.doi.org/10.1136/jitc-2021-002780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671984/
https://www.ncbi.nlm.nih.gov/pubmed/34907028
http://dx.doi.org/10.1136/jitc-2021-002780

Ejemplares similares