Integrated single-cell sequencing of 5-hydroxymethylcytosine and genomic DNA using scH&G-seq

The asymmetric distribution of 5-hydroxymethylcytosine (5hmC) between two DNA strands of a chromosome enables endogenous reconstruction of cellular lineages at an individual-cell-division resolution. Further, when integrated with data on genomic variants to infer clonal lineages, this combinatorial...

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Detalles Bibliográficos
Autores principales: Chialastri, Alex, Wangsanuwat, Chatarin, Dey, Siddharth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672100/
https://www.ncbi.nlm.nih.gov/pubmed/34950891
http://dx.doi.org/10.1016/j.xpro.2021.101016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672100/
https://www.ncbi.nlm.nih.gov/pubmed/34950891
http://dx.doi.org/10.1016/j.xpro.2021.101016

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