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Effect of NPC1L1 and HMGCR Genetic Variants With Premature Triple-Vessel Coronary Disease

Background: Both Niemann-Pick C1-like 1 (NPC1L1) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) play a key role on dyslipidaemia. We aim to evaluate whether NPC1L1 and HMGCR genetic variants are associated with susceptibility of premature triple-vessel disease (PTVD). Methods: Four sing...

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Detalles Bibliográficos
Autores principales: Zhao, Xueyan, Xu, Jingjing, Tang, Xiaofang, Huang, Keyong, Li, Jiawen, Liu, Ru, Jiang, Lin, Zhang, Yin, Wang, Dong, Sun, Kai, Xu, Bo, Zhao, Wei, Hui, Rutai, Gao, Runlin, Song, Lei, Yuan, Jinqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672111/
https://www.ncbi.nlm.nih.gov/pubmed/34926596
http://dx.doi.org/10.3389/fcvm.2021.704501