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Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons

The decline in brain function during aging is one of the most critical health problems nowadays. Although senescent astrocytes have been found in old-age brains and neurodegenerative diseases, their impact on the function of other cerebral cell types is unknown. The aim of this study was to evaluate...

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Detalles Bibliográficos
Autores principales: Morales-Rosales, Sandra Lizbeth, Santín-Márquez, Roberto, Posadas-Rodriguez, Pedro, Rincon-Heredia, Ruth, Montiel, Teresa, Librado-Osorio, Raúl, Luna-López, Armando, Rivero-Segura, Nadia Alejandra, Torres, Claudio, Cano-Martínez, Agustina, Silva-Palacios, Alejandro, Cortés-Hernández, Paulina, Morán, Julio, Massieu, Lourdes, Konigsberg, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672143/
https://www.ncbi.nlm.nih.gov/pubmed/34924995
http://dx.doi.org/10.3389/fnagi.2021.766306