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Upregulation of IRF9 Contributes to Pulmonary Artery Smooth Muscle Cell Proliferation During Pulmonary Arterial Hypertension

Abnormal proliferation of pulmonary artery smooth muscle cells (PASMCs) is a critical pathological feature in the pathogenesis of pulmonary arterial hypertension (PAH), but the regulatory mechanisms remain largely unknown. Herein, we demonstrated that interferon regulatory factor 9 (IRF9) accelerate...

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Detalles Bibliográficos
Autores principales: Chen, Yong-Jie, Li, Yi, Guo, Xian, Huo, Bo, Chen, Yue, He, Yi, Xiao, Rui, Zhu, Xue-Hai, Jiang, Ding-Sheng, Wei, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672195/
https://www.ncbi.nlm.nih.gov/pubmed/34925032
http://dx.doi.org/10.3389/fphar.2021.773235