Cargando…

Upregulation of IRF9 Contributes to Pulmonary Artery Smooth Muscle Cell Proliferation During Pulmonary Arterial Hypertension

Abnormal proliferation of pulmonary artery smooth muscle cells (PASMCs) is a critical pathological feature in the pathogenesis of pulmonary arterial hypertension (PAH), but the regulatory mechanisms remain largely unknown. Herein, we demonstrated that interferon regulatory factor 9 (IRF9) accelerate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yong-Jie, Li, Yi, Guo, Xian, Huo, Bo, Chen, Yue, He, Yi, Xiao, Rui, Zhu, Xue-Hai, Jiang, Ding-Sheng, Wei, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672195/ https://www.ncbi.nlm.nih.gov/pubmed/34925032 http://dx.doi.org/10.3389/fphar.2021.773235

Ejemplares similares

Cysteine-rich 61 (Cyr61) upregulated in pulmonary arterial hypertension promotes the proliferation of pulmonary artery smooth muscle cells
por: Gao, Lan, et al.
Publicado: (2017)

Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension
por: Courboulin, Audrey, et al.
Publicado: (2011)

Endogenous Estrogen Attenuates Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Vasoconstriction and Pulmonary Arterial Smooth Muscle Cells Proliferation
por: Xu, Dunquan, et al.
Publicado: (2013)

Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway
por: Peng, Linqian, et al.
Publicado: (2022)

Transgelin exacerbates pulmonary artery smooth muscle cell dysfunction in shunt‐related pulmonary arterial hypertension
por: Zhou, Jing‐jing, et al.
Publicado: (2022)

Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation
por: Zhang, Lei, et al.
Publicado: (2020)

Zinc-mediated activation of CREB pathway in proliferation of pulmonary artery smooth muscle cells in pulmonary hypertension
por: Xiao, Genfa, et al.
Publicado: (2021)

Glycogen Synthase Kinase 3beta Contributes to Proliferation of Arterial Smooth Muscle Cells in Pulmonary Hypertension
por: Sklepkiewicz, Piotr, et al.
Publicado: (2011)

Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats
por: Tong, Yi, et al.
Publicado: (2018)

Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension
por: Wilson, Jamie L., et al.
Publicado: (2019)

Extracellular vesicles derived from endothelial cells in hypoxia contribute to pulmonary artery smooth muscle cell proliferation in‐vitro and pulmonary hypertension in mice
por: Chen, Tianji, et al.
Publicado: (2022)

The Role and Regulation of Pulmonary Artery Smooth Muscle Cells in Pulmonary Hypertension
por: He, Shixin, et al.
Publicado: (2020)

Dapagliflozin has No Protective Effect on Experimental Pulmonary Arterial Hypertension and Pulmonary Trunk Banding Rat Models
por: Li, Huayang, et al.
Publicado: (2021)

The Na(+)/H(+) exchanger contributes to increased smooth muscle proliferation and migration in a rat model of pulmonary arterial hypertension
por: Huetsch, John C., et al.
Publicado: (2016)

Traditional Chinese medicine monomers: Targeting pulmonary artery smooth muscle cells proliferation to treat pulmonary hypertension
por: Yang, Xiuli, et al.
Publicado: (2023)

JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension
por: Zhang, Chen, et al.
Publicado: (2023)

Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice
por: Lakhal-Littleton, Samira, et al.
Publicado: (2019)

Adenosine Receptors As Drug Targets for Treatment of Pulmonary Arterial Hypertension
por: Alencar, Allan K. N., et al.
Publicado: (2017)

Therapy for Pulmonary Arterial Hypertension: Glance on Nitric Oxide Pathway
por: Tettey, Abraham, et al.
Publicado: (2021)

Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension
por: Wang, Ai-Ping, et al.
Publicado: (2021)

Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy
por: Lyle, Melissa A., et al.
Publicado: (2017)

Effect of EZH2 on pulmonary artery smooth muscle cell migration in pulmonary hypertension
por: Wang, Ying, et al.
Publicado: (2021)

Pharmacological Alteration of Cellular Mechanical Properties in Pulmonary Arterial Smooth Muscle Cells of Idiopathic Pulmonary Arterial Hypertension
por: Katsuragi, Shinichi, et al.
Publicado: (2021)

Synemin promotes pulmonary artery smooth muscle cell phenotypic switch in shunt‐induced pulmonary arterial hypertension
por: Zhou, Jingjing
Publicado: (2022)

New hope for Nutlin-3a therapy for pulmonary arterial hypertension
por: Fukumoto, Jutaro, et al.
Publicado: (2013)

Traditional Herbal Medicine Discovery for the Treatment and Prevention of Pulmonary Arterial Hypertension
por: Xue, Zhifeng, et al.
Publicado: (2021)

Survivin inhibition with YM155 ameliorates experimental pulmonary arterial hypertension
por: Blanco, Isabel, et al.
Publicado: (2023)

Cost-effectiveness analysis of selexipag for the combined treatment of pulmonary arterial hypertension
por: Dong, Wenxing, et al.
Publicado: (2023)

Akt-Dependent Glycolysis-Driven Lipogenesis Supports Proliferation and Survival of Human Pulmonary Arterial Smooth Muscle Cells in Pulmonary Hypertension
por: Jiang, Lifeng, et al.
Publicado: (2022)

Role of smooth muscle cell p53 in pulmonary arterial hypertension
por: Wakasugi, Takayuki, et al.
Publicado: (2019)

Supplementation with Tex261 provides a possible preventive treatment for hypoxic pulmonary artery hypertension
por: Chen, Shaokun, et al.
Publicado: (2022)

Paeoniflorin Inhibits Pulmonary Artery Smooth Muscle Cells Proliferation via Upregulating A(2B) Adenosine Receptor in Rat
por: Qian, Guoqing, et al.
Publicado: (2013)

Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2
por: Sun, Zengxian, et al.
Publicado: (2022)

Upregulated Genes In Sporadic, Idiopathic Pulmonary Arterial Hypertension
por: Edgar, Alasdair J, et al.
Publicado: (2006)

The Transition From Ambrisentan to Macitentan in Patients With Pulmonary Arterial Hypertension: A Real-word Prospective Study
por: Chen, Yusi, et al.
Publicado: (2022)

STIM2 contributes to enhanced store-operated Ca(2+) entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
por: Song, Michael Y., et al.
Publicado: (2011)

Long non-coding RNA CASC2 suppresses pulmonary artery smooth muscle cell proliferation and phenotypic switch in hypoxia-induced pulmonary hypertension
por: Gong, Junsong, et al.
Publicado: (2019)

Leflunomide-induced pulmonary arterial hypertension in a young man with nephrotic syndrome: A case report
por: Luo, Xiaoqin, et al.
Publicado: (2022)

Smooth muscle Rac1 contributes to pulmonary hypertension
por: Dilasser, Florian, et al.
Publicado: (2022)

piRNA‐63076 contributes to pulmonary arterial smooth muscle cell proliferation through acyl‐CoA dehydrogenase
por: Ma, Cui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dqcolsts728nkd2t91da5c1l45