Inhibition of Sirt2 Alleviates Fibroblasts Activation and Pulmonary Fibrosis via Smad2/3 Pathway

Idiopathic pulmonary fibrosis (IPF) is a fatal disease with unknown cause and limited treatment options. Its mechanism needs to be further explored. Sirtuin2 (Sirt2), a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, has been proved to be involved in the fibrosis and inflammation in t...

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Detalles Bibliográficos
Autores principales: Gong, Hui, Zheng, Chenyi, Lyu, Xing, Dong, Lini, Tan, Shengyu, Zhang, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672210/
https://www.ncbi.nlm.nih.gov/pubmed/34925016
http://dx.doi.org/10.3389/fphar.2021.756131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672210/
https://www.ncbi.nlm.nih.gov/pubmed/34925016
http://dx.doi.org/10.3389/fphar.2021.756131

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