Overexpression of Cystine/Glutamate Antiporter xCT Correlates with Nutrient Flexibility and ZEB1 Expression in Highly Clonogenic Glioblastoma Stem-like Cells (GSCs)

SIMPLE SUMMARY: Glioblastoma (GBM) is the most aggressive form of glioma (WHO grade IV), and mounting evidence suggests that glioblastoma stem-like cells (GSCs) play an important role in tumor growth and response to therapy. In the current study, we sought to understand the metabolic dependencies of...

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Detalles Bibliográficos
Autores principales: Koch, Katharina, Hartmann, Rudolf, Suwala, Abigail Kora, Rios, Dayana Herrera, Kamp, Marcel Alexander, Sabel, Michael, Steiger, Hans-Jakob, Willbold, Dieter, Sharma, Amit, Kahlert, Ulf Dietrich, Maciaczyk, Jarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672273/
https://www.ncbi.nlm.nih.gov/pubmed/34885110
http://dx.doi.org/10.3390/cancers13236001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672273/
https://www.ncbi.nlm.nih.gov/pubmed/34885110
http://dx.doi.org/10.3390/cancers13236001

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