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JAK2 deficiency improves erectile function in diabetic mice through attenuation of oxidative stress, apoptosis, and fibrosis

BACKGROUND: Janus kinase 2 (JAK2) is activated in diabetic mellitus (DM) conditions and may enhance oxidative stress, apoptosis and fibrosis in many tissues. Whether JAK2 activation is involved in the occurrence of diabetic erectile dysfunction (ED) is unknown. OBJECTIVES: We performed this study to...

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Detalles Bibliográficos
Autores principales: Li, Hao, Xu, Wenchao, Liu, Xiaming, Wang, Tao, Wang, Shaogang, Liu, Jihong, Jiang, Hongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672361/
https://www.ncbi.nlm.nih.gov/pubmed/34085398
http://dx.doi.org/10.1111/andr.13061