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Porphyromonas gingivalis-Induced Cognitive Impairment Is Associated With Gut Dysbiosis, Neuroinflammation, and Glymphatic Dysfunction

BACKGROUND: Periodontal pathogen and gut microbiota are closely associated with the pathogenesis of Alzheimer’s disease (AD). Porphyromonas gingivalis (Pg), the keystone periodontal pathogen, can induce cognitive impairment. The gut has a connection and communication with the brain, which is an impo...

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Detalles Bibliográficos
Autores principales: Chi, Li, Cheng, Xiao, Lin, Lishan, Yang, Tao, Sun, Jianbo, Feng, Yiwei, Liang, Fengyin, Pei, Zhong, Teng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672439/
https://www.ncbi.nlm.nih.gov/pubmed/34926316
http://dx.doi.org/10.3389/fcimb.2021.755925