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Comparison of plasma neurofilament light and total tau as neurodegeneration markers: associations with cognitive and neuroimaging outcomes

BACKGROUND: Total tau protein (T-Tau) and neurofilament light chain (NfL) have emerged as candidate plasma biomarkers of neurodegeneration, but studies have not compared how these biomarkers cross-sectionally or longitudinally associate with cognitive and neuroimaging measures. We therefore compared...

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Detalles Bibliográficos
Autores principales: Marks, Jordan D., Syrjanen, Jeremy A., Graff-Radford, Jonathan, Petersen, Ronald C., Machulda, Mary M., Campbell, Michelle R., Algeciras-Schimnich, Alicia, Lowe, Val, Knopman, David S., Jack, Clifford R., Vemuri, Prashanthi, Mielke, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672619/
https://www.ncbi.nlm.nih.gov/pubmed/34906229
http://dx.doi.org/10.1186/s13195-021-00944-y