A benchmark of structural variation detection by long reads through a realistic simulated model

Accurate simulations of structural variation distributions and sequencing data are crucial for the development and benchmarking of new tools. We develop Sim-it, a straightforward tool for the simulation of both structural variation and long-read data. These simulations from Sim-it reveal the strengt...

Descripción completa

Detalles Bibliográficos
Autores principales: Dierckxsens, Nicolas, Li, Tong, Vermeesch, Joris R., Xie, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672642/
https://www.ncbi.nlm.nih.gov/pubmed/34911553
http://dx.doi.org/10.1186/s13059-021-02551-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672642/
https://www.ncbi.nlm.nih.gov/pubmed/34911553
http://dx.doi.org/10.1186/s13059-021-02551-4

Ejemplares similares