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“P(2)RY(8)-son” break of tolerance promotes SLE
In this issue of JEM, He et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20211004) associate novel P2RY8 genetic variants to lupus, expanding the field of monogenic autoimmunity. The authors demonstrate that P2RY8 prevents the expansion of DNA-reactive B cells by restraining B cell mobility a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672645/ https://www.ncbi.nlm.nih.gov/pubmed/34901992 http://dx.doi.org/10.1084/jem.20211972 |