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DE-STRESS: a user-friendly web application for the evaluation of protein designs

De novo protein design is a rapidly growing field, and there are now many interesting and useful examples of designed proteins in the literature. However, most designs could be classed as failures when characterised in the lab, usually as a result of low expression, misfolding, aggregation or lack o...

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Detalles Bibliográficos
Autores principales: Stam, Michael J, Wood, Christopher W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672653/
https://www.ncbi.nlm.nih.gov/pubmed/34908138
http://dx.doi.org/10.1093/protein/gzab029