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Behavioral and Molecular Analysis of Antioxidative Potential of Rosmarinic Acid Against Methamphetamine-induced Augmentation of Casp3a mRNA in the Zebrafish Brain

INTRODUCTION: Methamphetamine (MA) acts as a powerful oxidant agent, while Rosmarinic Acid (RA) is an effective herbal antioxidant. Oxidative stress-mediated by MA results in apoptosis, and caspase-3 is one of the critical enzymes in the apoptosis process. MA can epigenetically alter gene regulation...

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Detalles Bibliográficos
Autores principales: Nikshenas Shahrestani, Vida, Haddadi, Mohammad, Samzadeh Kermani, Ali Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672665/
https://www.ncbi.nlm.nih.gov/pubmed/34925721
http://dx.doi.org/10.32598/bcn.12.2.1777.1