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Stereodivergent synthesis via iridium-catalyzed asymmetric double allylic alkylation of cyanoacetate

Methods that enable the rapid construction of multiple C–C bonds using a single catalyst with high diastereo- and enantio-control are particularly valuable in organic synthesis. Here, we report an Ir-catalyzed double allylic alkylation reaction in which bisnucleophilic cyanoacetate reacted successio...

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Detalles Bibliográficos
Autores principales: Shen, Chong, Cheng, Xiang, Wei, Liang, Wang, Ruo-Qing, Wang, Chun-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672708/
https://www.ncbi.nlm.nih.gov/pubmed/35024112
http://dx.doi.org/10.1039/d1sc06115a