Direct access to tetrasubstituted cyclopentenyl scaffolds through a diastereoselective isocyanide-based multicomponent reaction

An efficient strategy combining the stereocontrol of organocatalysis with the diversity-generating character of multicomponent reactions is described to produce structurally unique, tetrasubstituted cyclopentenyl frameworks. An asymmetric Michael addition–hemiacetalization between α-cyanoketones and...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, Vitor A., Lima, Rafaely N., Broterson, Yoisel B., Kawamura, Meire Y., Echemendía, Radell, de la Torre, Alexander F., Ferreira, Marco A. B., Rivera, Daniel G., Paixão, Marcio W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672720/
https://www.ncbi.nlm.nih.gov/pubmed/35024110
http://dx.doi.org/10.1039/d1sc04158d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672720/
https://www.ncbi.nlm.nih.gov/pubmed/35024110
http://dx.doi.org/10.1039/d1sc04158d

Ejemplares similares