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Direct access to tetrasubstituted cyclopentenyl scaffolds through a diastereoselective isocyanide-based multicomponent reaction

An efficient strategy combining the stereocontrol of organocatalysis with the diversity-generating character of multicomponent reactions is described to produce structurally unique, tetrasubstituted cyclopentenyl frameworks. An asymmetric Michael addition–hemiacetalization between α-cyanoketones and...

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Detalles Bibliográficos
Autores principales:	Fernandes, Vitor A., Lima, Rafaely N., Broterson, Yoisel B., Kawamura, Meire Y., Echemendía, Radell, de la Torre, Alexander F., Ferreira, Marco A. B., Rivera, Daniel G., Paixão, Marcio W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672720/ https://www.ncbi.nlm.nih.gov/pubmed/35024110 http://dx.doi.org/10.1039/d1sc04158d

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