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IL-4i1 Regulation of Immune Protection During Mycobacterium tuberculosis Infection

BACKGROUND: Interleukin 4 (IL-4i1)–induced gene 1 encodes L-phenylalanine oxidase that catabolizes phenylalanine into phenylpyruvate. IL-4i1 is mainly expressed by antigen-presenting cells (APCs), inhibits T-cell proliferation, regulates B-cell activation, modulates T cell responses, and drives macr...

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Detalles Bibliográficos
Autores principales: Hlaka, Lerato, Ozturk, Mumin, Chia, Julius E, Jones, Shelby-Sara, Pillay, Shandre, Poswayo, Sibongiseni K L, Mpotje, Thabo, Nono, Justin K, Simelane, Simphiwe R N, Parihar, Suraj P, Roy, Sugata, Suzuki, Harukazu, Brombacher, Frank, Guler, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672763/
https://www.ncbi.nlm.nih.gov/pubmed/34739044
http://dx.doi.org/10.1093/infdis/jiab558