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IL-4i1 Regulation of Immune Protection During Mycobacterium tuberculosis Infection
BACKGROUND: Interleukin 4 (IL-4i1)–induced gene 1 encodes L-phenylalanine oxidase that catabolizes phenylalanine into phenylpyruvate. IL-4i1 is mainly expressed by antigen-presenting cells (APCs), inhibits T-cell proliferation, regulates B-cell activation, modulates T cell responses, and drives macr...
Autores principales: | Hlaka, Lerato, Ozturk, Mumin, Chia, Julius E, Jones, Shelby-Sara, Pillay, Shandre, Poswayo, Sibongiseni K L, Mpotje, Thabo, Nono, Justin K, Simelane, Simphiwe R N, Parihar, Suraj P, Roy, Sugata, Suzuki, Harukazu, Brombacher, Frank, Guler, Reto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672763/ https://www.ncbi.nlm.nih.gov/pubmed/34739044 http://dx.doi.org/10.1093/infdis/jiab558 |
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