α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease

The cell‐to‐cell transfer of α‐synuclein (α‐Syn) greatly contributes to Parkinson's disease (PD) pathogenesis and underlies the spread of α‐Syn pathology. During this process, extracellular α‐Syn can activate microglia and neuroinflammation, which plays an important role in PD. However, the eff...

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Detalles Bibliográficos
Autores principales: Tu, Hai‐Yue, Yuan, Bao‐Shi, Hou, Xiao‐Ou, Zhang, Xiao‐Jun, Pei, Chong‐Shuang, Ma, Ya‐Ting, Yang, Ya‐Ping, Fan, Yi, Qin, Zheng‐Hong, Liu, Chun‐Feng, Hu, Li‐Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672776/
https://www.ncbi.nlm.nih.gov/pubmed/34811872
http://dx.doi.org/10.1111/acel.13522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672776/
https://www.ncbi.nlm.nih.gov/pubmed/34811872
http://dx.doi.org/10.1111/acel.13522

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