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miR‐125a‐5p increases cellular DNA damage of aging males and perturbs stage‐specific embryo development via Rbm38‐p53 signaling

An increasing number of men are fathering children at an older age than in the past. While advanced maternal age has long been recognized as a risk factor for adverse reproductive outcomes, the influence of paternal age on reproduction is incompletely comprehended. Herein, we found that miR‐125a‐5p...

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Detalles Bibliográficos
Autores principales: Liang, Kuan, Yao, Liangyu, Wang, Shuxian, Zheng, Lu, Qian, Zhang, Ge, Yifeng, Chen, Li, Cheng, Xi, Ma, Rujun, Li, Chuwei, Jing, Jun, Yang, Yang, Yu, Wanwan, Xue, Tongmin, Chen, Qiwei, Cao, Siyuan, Ma, Jinzhao, Yao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672779/
https://www.ncbi.nlm.nih.gov/pubmed/34751998
http://dx.doi.org/10.1111/acel.13508