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Nogo receptor impairs the clearance of fibril amyloid‐β by microglia and accelerates Alzheimer’s‐like disease progression

Alzheimer's disease (AD) is characterized by the progressive accumulation of β‐amyloid (Aβ)‐containing amyloid plaques, and microglia play a critical role in mediating Aβ clearance. Mounting evidence has confirmed that the ability of microglia in clearing Aβ decreased with aging and AD progress...

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Detalles Bibliográficos
Autores principales: Wang, Jianing, Qin, Xiaoying, Sun, Hao, He, Meijun, Lv, Qunyu, Gao, Congcong, He, Xinran, Liao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672787/
https://www.ncbi.nlm.nih.gov/pubmed/34821024
http://dx.doi.org/10.1111/acel.13515