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Mitochondrial aconitase 1 regulates age‐related memory impairment via autophagy/mitophagy‐mediated neural plasticity in middle‐aged flies

Age‐related memory impairment (AMI) occurs in many species, including humans. The underlying mechanisms are not fully understood. In wild‐type Drosophila (w(1118) ), AMI appears in the form of a decrease in learning (3‐min memory) from middle age (30 days after eclosion [DAE]). We performed in vivo,...

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Detalles Bibliográficos
Autores principales: Cho, Yun‐Ho, Kim, Gye‐Hyeong, Park, Joong‐Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672789/
https://www.ncbi.nlm.nih.gov/pubmed/34799973
http://dx.doi.org/10.1111/acel.13520