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Selective oxidative stress induces dual damage to telomeres and mitochondria in human T cells

Oxidative stress caused by excess reactive oxygen species (ROS) accelerates telomere erosion and mitochondrial injury, leading to impaired cellular functions and cell death. Whether oxidative stress‐mediated telomere erosion induces mitochondrial injury, or vice versa, in human T cells—the major eff...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Lu, Zeyuan, Zhao, Juan, Schank, Madison, Cao, Dechao, Dang, Xindi, Nguyen, Lam Nhat, Nguyen, Lam Ngoc Thao, Khanal, Sushant, Zhang, Jinyu, Wu, Xiao Y., El Gazzar, Mohamed, Ning, Shunbin, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672791/
https://www.ncbi.nlm.nih.gov/pubmed/34752684
http://dx.doi.org/10.1111/acel.13513