Cinobufagin Is a Selective Anti-Cancer Agent against Tumors with EGFR Amplification and PTEN Deletion

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor, and almost half of the patients carrying EGFR-driven tumor with PTEN deficiency are resistant to EGFR-targeted therapy. EGFR amplification and/or mutation is reported in various epithelial tumors. This series of studies aime...

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Detalles Bibliográficos
Autores principales: He, Kunyan, Wang, Guang-Xing, Zhao, Li-Nan, Cui, Xiao-Fang, Su, Xian-Bin, Shi, Yi, Xie, Tian-Pei, Hou, Shang-Wei, Han, Ze-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672866/
https://www.ncbi.nlm.nih.gov/pubmed/34925034
http://dx.doi.org/10.3389/fphar.2021.775602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672866/
https://www.ncbi.nlm.nih.gov/pubmed/34925034
http://dx.doi.org/10.3389/fphar.2021.775602

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