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Combined Transcriptome and Proteome Profiling for Role of pfEMP1 in Antimalarial Mechanism of Action of Dihydroartemisinin

Malaria parasites induce morphological and biochemical changes in the membranes of parasite-infected red blood cells (iRBCs) for propagation. Artemisinin combination therapies are the first-line antiplasmodials in countries of endemicity. However, the mechanism of action of artemisinin is unclear, a...

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Detalles Bibliográficos
Autores principales: Chen, Lina, Zheng, Zhongyuan, Liu, Hui, Wang, Xi, Qu, Shuiqing, Yang, Yuanmin, Deng, Shuoqiu, Zhang, Yu, Tuo, Liu, Zhao, Yongdan, Li, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672878/
https://www.ncbi.nlm.nih.gov/pubmed/34908430
http://dx.doi.org/10.1128/Spectrum.01278-21