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Bacteriophage Therapy for the Prevention and Treatment of Fracture-Related Infection Caused by Staphylococcus aureus: a Preclinical Study

Although several studies have shown promising clinical outcomes of phage therapy in patients with orthopedic device-related infections, questions remain regarding the optimal application protocol, systemic effects, and the impact of the immune response. This study provides a proof-of-concept of phag...

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Detalles Bibliográficos
Autores principales: Onsea, Jolien, Post, Virginia, Buchholz, Tim, Schwegler, Hella, Zeiter, Stephan, Wagemans, Jeroen, Pirnay, Jean-Paul, Merabishvili, Maya, D’Este, Matteo, Rotman, Stijn G., Trampuz, Andrej, Verhofstad, Michael H. J., Obremskey, William T., Lavigne, Rob, Richards, R. Geoff, Moriarty, T. Fintan, Metsemakers, Willem-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672900/
https://www.ncbi.nlm.nih.gov/pubmed/34908439
http://dx.doi.org/10.1128/spectrum.01736-21