Genetic Characterization and Passage Instability of a Hybrid Plasmid Co-Harboring bla(IMP-4) and bla(NDM-1) Reveal the Contribution of Insertion Sequences During Plasmid Formation and Evolution

Carbapenemase is the predominant enzyme in the mechanism leading to Enterobacterales resistance to carbapenems, but only a limited number of isolates harbor double classes/types of carbapenemase. Here, an IMP-4 and NDM-1 producer named Klebsiella michiganensis 7525 is reported, and the co-harboring...

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Detalles Bibliográficos
Autores principales: Li, Xi, He, Jintao, Jiang, Yan, Peng, Minfei, Yu, Yunsong, Fu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672901/
https://www.ncbi.nlm.nih.gov/pubmed/34908434
http://dx.doi.org/10.1128/Spectrum.01577-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672901/
https://www.ncbi.nlm.nih.gov/pubmed/34908434
http://dx.doi.org/10.1128/Spectrum.01577-21

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