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Ubiquitinated Hepatitis D Antigen-Loaded Microvesicles Induce a Potent Specific Cellular Immune Response to Inhibit HDV Replication in Vivo

Hepatitis D is the most severe form of human viral hepatitis and currently lacks an efficient therapy. Dendritic cell-derived exosomes (Dexs) have been found to induce immune responses capable of eliminating viruses. However, the therapeutic potential of antigen-loaded exosomes in hepatitis D is sti...

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Detalles Bibliográficos
Autores principales: Yao, Ting, Lv, Mengjiao, Ma, Siyuan, Chen, Jinmei, Zhang, Yi, Yu, Yongsheng, Zang, Guoqing, Chen, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672902/
https://www.ncbi.nlm.nih.gov/pubmed/34908456
http://dx.doi.org/10.1128/Spectrum.01024-21