Repurposing Approved Drugs as Fluoroquinolone Potentiators to Overcome Efflux Pump Resistance in Staphylococcus aureus

Staphylococcus aureus is a versatile human commensal bacteria and pathogen that causes various community and hospital-acquired infections. The S. aureus efflux pump NorA which belongs to the major facilitator superfamily, confers resistance to a range of substrates. Many efflux pump inhibitors (EPIs...

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Detalles Bibliográficos
Autores principales: Mahey, Nisha, Tambat, Rushikesh, Chandal, Nishtha, Verma, Dipesh Kumar, Thakur, Krishan Gopal, Nandanwar, Hemraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672906/
https://www.ncbi.nlm.nih.gov/pubmed/34908453
http://dx.doi.org/10.1128/Spectrum.00951-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672906/
https://www.ncbi.nlm.nih.gov/pubmed/34908453
http://dx.doi.org/10.1128/Spectrum.00951-21

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