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Repurposing Approved Drugs as Fluoroquinolone Potentiators to Overcome Efflux Pump Resistance in Staphylococcus aureus
Staphylococcus aureus is a versatile human commensal bacteria and pathogen that causes various community and hospital-acquired infections. The S. aureus efflux pump NorA which belongs to the major facilitator superfamily, confers resistance to a range of substrates. Many efflux pump inhibitors (EPIs...
Autores principales: | Mahey, Nisha, Tambat, Rushikesh, Chandal, Nishtha, Verma, Dipesh Kumar, Thakur, Krishan Gopal, Nandanwar, Hemraj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672906/ https://www.ncbi.nlm.nih.gov/pubmed/34908453 http://dx.doi.org/10.1128/Spectrum.00951-21 |
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