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Immunosenescence and Autoimmunity: Exploiting the T-Cell Receptor Repertoire to Investigate the Impact of Aging on Multiple Sclerosis

T-cell receptor (TCR) repertoire diversity is a determining factor for the immune system capability in fighting infections and preventing autoimmunity. During life, the TCR repertoire diversity progressively declines as a physiological aging progress. The investigation of TCR repertoire dynamics ove...

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Detalles Bibliográficos
Autores principales: Amoriello, Roberta, Mariottini, Alice, Ballerini, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673061/
https://www.ncbi.nlm.nih.gov/pubmed/34925384
http://dx.doi.org/10.3389/fimmu.2021.799380