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Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide

The TLR4-interacting SPA4 peptide suppresses inflammation. We assessed the structural and physicochemical properties and binding of SPA4 peptide to TLR4–MD2. We also studied the changes at the whole transcriptome level, cell morphology, viability, secreted cytokines and chemokines, and cell influx i...

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Detalles Bibliográficos
Autores principales: Awasthi, Shanjana, Kumar, Gaurav, Ramani, Vijay, Awasthi, Vibhudutta, Rodgers, Karla K., Xie, Jun, Beierle, Jacob, Kyere-Davies, Gertrude, Singh, Bhupinder, Rahman, Negar, Chowdhury, Asif Alam, Chataut, Neha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673433/
https://www.ncbi.nlm.nih.gov/pubmed/34429343
http://dx.doi.org/10.4049/immunohorizons.2100067