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Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide
The TLR4-interacting SPA4 peptide suppresses inflammation. We assessed the structural and physicochemical properties and binding of SPA4 peptide to TLR4–MD2. We also studied the changes at the whole transcriptome level, cell morphology, viability, secreted cytokines and chemokines, and cell influx i...
Autores principales: | Awasthi, Shanjana, Kumar, Gaurav, Ramani, Vijay, Awasthi, Vibhudutta, Rodgers, Karla K., Xie, Jun, Beierle, Jacob, Kyere-Davies, Gertrude, Singh, Bhupinder, Rahman, Negar, Chowdhury, Asif Alam, Chataut, Neha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673433/ https://www.ncbi.nlm.nih.gov/pubmed/34429343 http://dx.doi.org/10.4049/immunohorizons.2100067 |
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