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Negative Transpulmonary Pressure Disrupts Airway Morphogenesis by Suppressing Fgf10

Mechanical forces are increasingly recognized as important determinants of cell and tissue phenotype and also appear to play a critical role in organ development. During the fetal stages of lung morphogenesis, the pressure of the fluid within the lumen of the airways is higher than that within the c...

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Detalles Bibliográficos
Autores principales: Stanton, Alice E., Goodwin, Katharine, Sundarakrishnan, Aswin, Jaslove, Jacob M., Gleghorn, Jason P., Pavlovich, Amira L., Nelson, Celeste M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673560/
https://www.ncbi.nlm.nih.gov/pubmed/34926440
http://dx.doi.org/10.3389/fcell.2021.725785