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Imperatorin inhibits mitogen‐activated protein kinase and nuclear factor kappa‐B signaling pathways and alleviates neuroinflammation in ischemic stroke

AIMS: Microglia‐mediated neuroinflammation plays an important role in the pathological process of ischemic stroke, and the effect of imperatorin on post‐stroke neuroinflammation is not fully understood. METHODS: Primary microglia were treated with imperatorin for 2 h followed by LPS (100 ng/ml) for...

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Detalles Bibliográficos
Autores principales: Ge, Jian‐wei, Deng, Shi‐ji, Xue, Zhi‐wei, Liu, Pin‐yi, Yu, Lin‐jie, Li, Jiang‐nan, Xia, Sheng‐nan, Gu, Yue, Bao, Xin‐yu, Lan, Zhen, Xu, Yun, Zhu, Xiao‐lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673701/
https://www.ncbi.nlm.nih.gov/pubmed/34674376
http://dx.doi.org/10.1111/cns.13748