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Amyotrophic lateral sclerosis (ALS) linked mutation in Ubiquilin 2 affects stress granule assembly via TIA‐1

AIMS: The ubiquilin‐like protein ubiquilin 2 (UBQLN2) is associated with amyotrophic lateral sclerosis and frontotemporal degeneration (ALS/FTD). The biological function of UBQLN2 has previously been shown to be related to stress granules (SGs). In this study, we aimed to clarify the regulatory rela...

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Detalles Bibliográficos
Autores principales: Peng, Guangnan, Gu, Ao, Niu, Hongyan, Chen, Linlin, Chen, Yan, Zhou, Miaojin, Zhang, Yiti, Liu, Jie, Cai, Licong, Liang, Desheng, Liu, Xionghao, Liu, Mujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673703/
https://www.ncbi.nlm.nih.gov/pubmed/34750982
http://dx.doi.org/10.1111/cns.13757