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Pharmacological inhibition of epidermal growth factor receptor attenuates intracranial aneurysm formation by modulating the phenotype of vascular smooth muscle cells

AIM: To study the effect of pharmacological inhibition of epidermal growth factor receptor (EGFR) on intracranial aneurysm (IA) initiation. METHODS: Human IA samples were analyzed for the expression of p‐EGFR and alpha smooth muscle actin (α‐SMA) by immunofluorescence (IF). Rat models of IA were est...

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Detalles Bibliográficos
Autores principales: Luo, Yin, Tang, Haishuang, Zhang, Zhaolong, Zhao, Rui, Wang, Chuanchuan, Hou, Wenguang, Huang, Qinghai, Liu, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673708/
https://www.ncbi.nlm.nih.gov/pubmed/34729926
http://dx.doi.org/10.1111/cns.13735