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Microglial deactivation by adeno‐associated virus expressing small‐hairpin GCH1 has protective effects against neuropathic pain development in a spinothalamic tract‐lesion model

AIMS: Neuropathic pain after spinal cord injury is one of the most difficult clinical problems after the loss of mobility, and pharmacological or neuromodulation therapy showed limited efficacy. In this study, we examine the possibility of pain modulation by a recombinant adeno‐associated virus (rAA...

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Detalles Bibliográficos
Autores principales: Jung, Hyun Ho, Koh, Chin Su, Park, Minkyung, Kim, Ji Hyun, Woo, Ha‐Na, Lee, Heuiran, Chang, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673712/
https://www.ncbi.nlm.nih.gov/pubmed/34845843
http://dx.doi.org/10.1111/cns.13751