CLN7 is an organellar chloride channel regulating lysosomal function

Neuronal ceroid lipofuscinoses (NCLs) are a group of autosomal recessive lysosomal storage diseases. One variant form of late-infantile NCL (vLINCL) is caused by mutations of a lysosomal membrane protein CLN7, the function of which has remained unknown. Here, we identified CLN7 as a novel endolysoso...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yayu, Zeng, Wenping, Lin, Bingqian, Yao, Yichuan, Li, Canjun, Hu, Wenqi, Wu, Haotian, Huang, Jiamin, Zhang, Mei, Xue, Tian, Ren, Dejian, Qu, Lili, Cang, Chunlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673761/
https://www.ncbi.nlm.nih.gov/pubmed/34910516
http://dx.doi.org/10.1126/sciadv.abj9608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673761/
https://www.ncbi.nlm.nih.gov/pubmed/34910516
http://dx.doi.org/10.1126/sciadv.abj9608

Ejemplares similares