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CLN7 is an organellar chloride channel regulating lysosomal function

Neuronal ceroid lipofuscinoses (NCLs) are a group of autosomal recessive lysosomal storage diseases. One variant form of late-infantile NCL (vLINCL) is caused by mutations of a lysosomal membrane protein CLN7, the function of which has remained unknown. Here, we identified CLN7 as a novel endolysoso...

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Detalles Bibliográficos
Autores principales:	Wang, Yayu, Zeng, Wenping, Lin, Bingqian, Yao, Yichuan, Li, Canjun, Hu, Wenqi, Wu, Haotian, Huang, Jiamin, Zhang, Mei, Xue, Tian, Ren, Dejian, Qu, Lili, Cang, Chunlei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673761/ https://www.ncbi.nlm.nih.gov/pubmed/34910516 http://dx.doi.org/10.1126/sciadv.abj9608

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