Exposure–safety analysis of QTc interval and transaminase levels following bedaquiline administration in patients with drug‐resistant tuberculosis

Bedaquiline (BDQ) has shown great value in the treatment of multidrug‐resistant tuberculosis (MDR‐TB) in recent years. However, exposure–safety relationships must be explored to extend the use of BDQ. Two reported safety findings for BDQ are prolongation of the QTc interval and elevation of transami...

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Detalles Bibliográficos
Autores principales: Tanneau, Lénaïg, Svensson, Elin M., Rossenu, Stefaan, Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674006/
https://www.ncbi.nlm.nih.gov/pubmed/34626526
http://dx.doi.org/10.1002/psp4.12722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674006/
https://www.ncbi.nlm.nih.gov/pubmed/34626526
http://dx.doi.org/10.1002/psp4.12722

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