Evaluation of the estimation and classification performance of NONMEM when applying mixture model for drug clearance

Maximum likelihood estimation of parameters involving mixture model is known to have significant and specific patterns of errors. Population pharmacokinetic (PopPK) modeling using NONMEM is no exception. A few relevant studies on estimation and classification performance were done, but a comprehensi...

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Detalles Bibliográficos
Autores principales: Hui, Ka Ho, Lam, Tai Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674007/
https://www.ncbi.nlm.nih.gov/pubmed/34648691
http://dx.doi.org/10.1002/psp4.12726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674007/
https://www.ncbi.nlm.nih.gov/pubmed/34648691
http://dx.doi.org/10.1002/psp4.12726

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