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Evaluation of the estimation and classification performance of NONMEM when applying mixture model for drug clearance
Maximum likelihood estimation of parameters involving mixture model is known to have significant and specific patterns of errors. Population pharmacokinetic (PopPK) modeling using NONMEM is no exception. A few relevant studies on estimation and classification performance were done, but a comprehensi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674007/ https://www.ncbi.nlm.nih.gov/pubmed/34648691 http://dx.doi.org/10.1002/psp4.12726 |