Activation of AdipoR1 with rCTRP9 Preserves BBB Integrity through the APPL1/AMPK/Nrf2 Signaling Pathway in ICH Mice

BACKGROUND: The disruption of the blood brain barrier (BBB) is the key factor leading to neurological impairment after intracerebral hemorrhage (ICH) injury. Adiponectin receptor 1 (AdipoR1) has an important effect contributing to the integrity of BBB. As a homologue of adiponectin, recombinant C1q/...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Kong, Fanping, Gong, Xiu, Guo, Zaiyu, Zhao, Lianhua, Wang, Sa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674037/
https://www.ncbi.nlm.nih.gov/pubmed/34925690
http://dx.doi.org/10.1155/2021/2801263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674037/
https://www.ncbi.nlm.nih.gov/pubmed/34925690
http://dx.doi.org/10.1155/2021/2801263

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