Paeoniflorin Improved Constipation in the Loperamide-Induced Rat Model via TGR5/TRPA1 Signaling-Mediated 5-Hydroxytryptamine Secretion

Slow transit constipation (STC) is a common type of constipation with a high incidence rate and a large number of patients. We aimed to investigate the therapeutic effects and potential mechanism of paeoniflorin (PAE) on loperamide-induced Sprague Dawley (SD) rat constipation models. Rats with loper...

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Detalles Bibliográficos
Autores principales: Zhan, Yu, Wen, Yong, Zhang, Liang-liang, Shen, Xu-long, Chen, Xiao-hui, Wu, Xiao-hai, Tang, Xue-gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674056/
https://www.ncbi.nlm.nih.gov/pubmed/34925531
http://dx.doi.org/10.1155/2021/6076293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674056/
https://www.ncbi.nlm.nih.gov/pubmed/34925531
http://dx.doi.org/10.1155/2021/6076293

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